The absorption of vitamin B12 in the megaloblastic anaemias.
نویسنده
چکیده
منابع مشابه
Effects of Vitamin B12 in Neonates and Young Infants
Vitamin B12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. Animal protein is the major dietary source of vitamin B12. Deficiency of vitamin B12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. Two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...
متن کاملThe vitamin B12 concentrations of serum and urine of normals and of patients with megaloblastic anaemias and other diseases.
Until recently deficiency of vitamin B12 in man could only be recognized by finding the characteristic clinical and haematological signs of the deficiency and by demonstrating that these signs were cured or relieved by treatment with the vitamin. Changes in the vitamin B12 content of the tissues could only be inferred from the responses of patients to treatment. The recent introduction of highl...
متن کاملThe present position of the treatment of megaloblastic anaemias.
A distinction must be drawn between megaloblastic and macrocytic anaemias. Not all macrocytic anaemias are megaloblastic and not all megaloblastic anaemias are macrocytic. The term macrocytosis refers to the size of red blood cells in the peripheral blood. The mean cell volume of packed red blood cells (haematocrit) may be greater than normal, or the diameters of a proportion of red blood cells...
متن کاملThe pathogenesis of megaloblastic anaemias and the value of vitamin B12.
Vitamin B,, 299 derive their vitamin B,, by absorption of microbially synthesized material from the gut. Carnivorous animals may derive theirs partly in this way and partly from their food. Vitamin B,, has been found in significant amounts in nature only in fermented materials like faeces and in animal products rich in protein. Liver and kidney appear to be the only relatively rich sources and ...
متن کاملVitamin B12, folic acid, and the nervous system.
There are many reasons for reviewing the neurology of vitamin-B12 and folic-acid deficiencies together, including the intimate relation between the metabolism of the two vitamins, their morphologically indistinguishable megaloblastic anaemias, and their overlapping neuropsychiatric syndromes and neuropathology, including their related inborn errors of metabolism. Folates and vitamin B12 have fu...
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ورودعنوان ژورنال:
- The Proceedings of the Nutrition Society
دوره 15 2 شماره
صفحات -
تاریخ انتشار 1956